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Cayman’s SARS-CoV-2 Spike-ACE2 Interaction Inhibitor Screening Assay Kit provides a robust and EAsy-to-use platform for identifying novel inhibitors of the SARS-CoV-2 spike and ACE2 interaction. The assay uses a recombinant rabbit Fc-tagged SARS-CoV-2 spike S1 RBD that binds to a plate precoated with a mouse anti-rabbit antibody. A recombinant His-tagged ACE2 protein binds the spike RBD and the complex is detected with an HRP-conjugated anti-His antibody, which is EAsily quantified by reading the absorbance at 450 nm. A control is included for competition of the SARS-CoV-2 spike RBD-ACE2 interaction.
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The V-PLEX Plus Metabolic Panel 1 Rat Kit from Meso Scale Diagnostics is a multiplex immunoassay kit that allows simultaneous measurement of 10 rat metabolic biomarkers (albumin ALP ALT AST BUN/urea creatinine glucose total protein and uric acid) from a single small sample volume This electrochemiluminescent assay utilizes multi-array technology and provides a rapid sensitive and reproducible method to profile the health and function of tissues and organs involved in metabolism and homeostasis in rat models With a streamlined workflow requiring only 50 L of sample this kit serves as an efficient tool for assessing toxicity and efficacy in preclinical drug development
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The Mesoscale K15596U-2 is a high-performance thermoelectric cooler for photonics and semiconductor applications offering precise temperature control It has a heat pumping capacity of 15 5W and a temperature differential of 70 C With dimensions of 30 x 30 x 3 4mm it requires 2 7V and handles up to 6A The K15596U-2 uses a Bi2Te3 thermoelectric module and aluminum nitride ceramic substrate for optimal performance It is ideal for stabilizing laser diodes and maintaining CCD sensors at precise temperatures
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Meso Scale Discovery provides V-PLEX immunoassay kits for mouse samples including cytokine chemokine growth factor and biomarker panels These multiplex assays detect multiple analytes from a single sample using MSD s SECTOR technology offering high sensitivity and a broad dynamic range Compatible with serum plasma and cell culture supernatants V-PLEX kits range from 2-plex to 10-plex with over 50 mouse analytes available The assays are fast simple and can be read on MSD s QuickPlex SQ 120 instruments efficiently generating biomarker data from limited samples
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The Meso Scale Discovery SARS-CoV-2 Spike P-1 V-PLEX Kit is an electrochemiluminescence immunoassay for the quantitative detection of SARS-CoV-2 Spike P-1 protein in serum plasma and cell culture supernatant samples The assay uses MSD s proprietary V-PLEX technology and provides high sensitivity a broad dynamic range and rapid results in under 3 hours The kit includes a 96-well plate coated with capture antibodies detection antibodies conjugated to an electrochemiluminescent label calibrators controls and sample diluent The assay has high specificity for SARS-CoV-2 Spike P-1 with no observed cross-reactivity
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
The Meso Scale Discovery V-PLEX Human VEGF Kit is a multiplex immunoassay that measures vascular endothelial growth factor (VEGF) in human serum plasma and cell culture supernatants The kit uses electrochemiluminescence (ECL) detection technology and provides high sensitivity a broad dynamic range and requires low sample volumes The V-PLEX VEGF Kit includes a 96-well plate coated with capture antibodies detection antibodies labeled with ECL tags calibrators diluent wash buffer read buffer and plate seals The assay has a typical sensitivity of 1 3 pg/mL and an upper limit of quantification of 10 000 pg/mL for VEGF
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A σ receptor ligand with anticancer and antiviral activites binds to σ1 and σ2 receptors (Kis 13 and 0.28 nM respectively in MCF-7 cell membranes) selective for σ1 and σ2 receptors over hERG channels (Ki 1000 nM) inhibits growth of MCF-7 and multidrug-resistant MCF-7/adr cells (IC50s 25 and 15 nM respectively) decreases basal P-gp levels in the same cells reduces SARS-CoV-2 infectivity in Vero E6 cells (IC90 278 nM)
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Immunogen/Preparation: This antibody was produced as a recombinant protein expressed in CHO cells using engineered constructs based on antibodies from COVID-19 patients. • Host: CHO cells • Species Reactivity: (+) Human • Applications: ELISA, IF, WB
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Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication
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